Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
wrnip1WRN helicase-interacting protein 1. (546 aa)    
Predicted Functional Partners:
wrn
WRN RecQ-like helicase.
  
 
 0.973
tnfb
Tumor necrosis factor b (TNF superfamily, member 2).
    
   0.933
rad18
RAD18 E3 ubiquitin protein ligase.
    
 
 0.913
LOC100334178
Uncharacterized protein.
    
 
 0.913
pcna
Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.
    
 
 0.892
pold2
Polymerase (DNA directed), delta 2, regulatory subunit.
    
 
 0.836
recql4
RecQ helicase-like 4.
  
 
 0.824
blm
BLM RecQ-like helicase.
  
 
 0.824
dna2
DNA replication helicase/nuclease 2.
   
 
 0.797
pold1
DNA polymerase.
    
 
 0.784
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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