STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ak2Adenylate kinase 2, mitochondrial; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism. Adenylate kinase activity is critical for regulation of the phosphate utilization and the AMP de novo biosynthesis pathways. Plays a key role in hematopoiesis. (241 aa)    
Predicted Functional Partners:
aprt
Adenine phosphoribosyltransferase.
  
 
 0.967
adka
Adenosine kinase a.
  
 0.965
adkb
Adenosine kinase b.
  
 0.965
adsl
Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
   
 0.953
ntpcr
Nucleoside-triphosphatase, cancer-related.
     
 0.931
zgc:110540
Deoxycytidine kinase 2.
   
 
 0.920
dck
Deoxycytidine kinase.
   
 
 0.920
tpk1
Thiamine pyrophosphokinase; Belongs to the thiamine pyrophosphokinase family.
     
 0.911
enpp1
Ectonucleotide pyrophosphatase/phosphodiesterase 1.
   
 
 0.906
nme4
Nucleoside diphosphate kinase.
  
 0.876
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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