| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| il10 | tp53 | ENSDARP00000098423 | ENSDARP00000116736 | Interleukin-10. | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of bax and fas antigen expression, or by repression of Bcl-2 expression. | 0.682 |
| il10 | tp53bp2a | ENSDARP00000098423 | ENSDARP00000010764 | Interleukin-10. | Tumor protein p53-binding protein, 2a. | 0.719 |
| ppp1caa | ppp1cb | ENSDARP00000002360 | ENSDARP00000109442 | Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. | Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. | 0.930 |
| ppp1caa | ppp1cbl | ENSDARP00000002360 | ENSDARP00000131101 | Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. | Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. | 0.930 |
| ppp1caa | ppp1cc | ENSDARP00000002360 | ENSDARP00000141959 | Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. | Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. | 0.863 |
| ppp1caa | tp53 | ENSDARP00000002360 | ENSDARP00000116736 | Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of bax and fas antigen expression, or by repression of Bcl-2 expression. | 0.490 |
| ppp1caa | tp53bp2a | ENSDARP00000002360 | ENSDARP00000010764 | Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. | Tumor protein p53-binding protein, 2a. | 0.748 |
| ppp1caa | wwtr1 | ENSDARP00000002360 | ENSDARP00000088304 | Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. | WW domain-containing transcription regulator 1. | 0.724 |
| ppp1caa | yap1 | ENSDARP00000002360 | ENSDARP00000089684 | Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. | Transcriptional coactivator YAP1; Transcriptional regulator which can act both as a coactivator and a corepressor and is the critical downstream regulatory target in the Hippo signaling pathway that plays a pivotal role in organ size control and tumor suppression by restricting proliferation and promoting apoptosis (By similarity). Required for expansion of the neural plate and neural plate border zone progenitor pools. Acts as a direct regulator of pax3 expression via interaction with tead1. Plays a key role in tissue tension and 3D tissue shape by regulating cortical actomyosin netwo [...] | 0.724 |
| ppp1cab | ppp1cb | ENSDARP00000087338 | ENSDARP00000109442 | Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. | Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. | 0.923 |
| ppp1cab | ppp1cbl | ENSDARP00000087338 | ENSDARP00000131101 | Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. | Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. | 0.923 |
| ppp1cab | ppp1cc | ENSDARP00000087338 | ENSDARP00000141959 | Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. | Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. | 0.863 |
| ppp1cab | tp53bp2a | ENSDARP00000087338 | ENSDARP00000010764 | Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. | Tumor protein p53-binding protein, 2a. | 0.748 |
| ppp1cab | wwtr1 | ENSDARP00000087338 | ENSDARP00000088304 | Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. | WW domain-containing transcription regulator 1. | 0.724 |
| ppp1cab | yap1 | ENSDARP00000087338 | ENSDARP00000089684 | Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. | Transcriptional coactivator YAP1; Transcriptional regulator which can act both as a coactivator and a corepressor and is the critical downstream regulatory target in the Hippo signaling pathway that plays a pivotal role in organ size control and tumor suppression by restricting proliferation and promoting apoptosis (By similarity). Required for expansion of the neural plate and neural plate border zone progenitor pools. Acts as a direct regulator of pax3 expression via interaction with tead1. Plays a key role in tissue tension and 3D tissue shape by regulating cortical actomyosin netwo [...] | 0.724 |
| ppp1cb | ppp1caa | ENSDARP00000109442 | ENSDARP00000002360 | Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. | Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. | 0.930 |
| ppp1cb | ppp1cab | ENSDARP00000109442 | ENSDARP00000087338 | Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. | Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. | 0.923 |
| ppp1cb | ppp1cc | ENSDARP00000109442 | ENSDARP00000141959 | Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. | Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. | 0.930 |
| ppp1cb | tp53 | ENSDARP00000109442 | ENSDARP00000116736 | Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of bax and fas antigen expression, or by repression of Bcl-2 expression. | 0.429 |
| ppp1cb | tp53bp2a | ENSDARP00000109442 | ENSDARP00000010764 | Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. | Tumor protein p53-binding protein, 2a. | 0.799 |
