Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
zc4h2Zinc finger C4H2 domain-containing protein; Plays a role in GABAergic and V2 interneurons differentiation. Involved in motoneuron development and in neuromuscular junction formation. (224 aa)    
Predicted Functional Partners:
rnf220a
Ring finger protein 220a.
    
 
 0.913
rnf220b
Ring finger protein 220b.
    
 
 0.913
acot9.1
Acyl-CoA thioesterase 9, tandem duplicate 1.
    
   0.753
acot9.2
Acyl-CoA thioesterase 9, tandem duplicate 2.
    
   0.753
ighmbp2
Immunoglobulin mu DNA-binding protein 2.
      
 0.721
LOC100332538
Endothelin-converting enzyme-like 1.
      
 0.662
nalcn
Sodium leak channel, non-selective.
      
 0.661
bicd2
Bicaudal D homolog 2 (Drosophila).
      
 0.640
hibch
3-hydroxyisobutyryl-CoA hydrolase, mitochondrial; Hydrolyzes 3-hydroxyisobutyryl-CoA (HIBYL-CoA), a saline catabolite. Has high activity toward isobutyryl-CoA. Could be an isobutyryl-CoA dehydrogenase that functions in valine catabolism. Also hydrolyzes 3-hydroxypropanoyl-CoA (By similarity); Belongs to the enoyl-CoA hydratase/isomerase family.
    
   0.630
BICD2
BICD cargo adaptor 2.
      
 0.626
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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