Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
avenApoptosis, caspase activation inhibitor. (322 aa)    
Predicted Functional Partners:
focad
Focadhesin.
    
 
 0.956
A2BGQ8_DANRE
N-acetylated alpha-linked acidic dipeptidase-like 1.
      
 0.738
ppp4r4
Protein phosphatase 4, regulatory subunit 4.
      
 0.720
bphl
Biphenyl hydrolase like.
      
 0.720
ubfd1
Ubiquitin family domain-containing 1.
      
 0.720
mbd5
Methyl-CpG-binding domain protein 5.
      
 0.666
tmem205
Transmembrane protein 205.
      
 0.662
apaf1
Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP (By similarity).
    
 
 0.605
rab12
RAB12, member RAS oncogene family.
      
 0.597
elp6
Elongator complex protein 6; Component of the RNA polymerase II elongator complex, a multiprotein complex associated with the RNA polymerase II (Pol II) holoenzyme, and which is involved in transcriptional elongation. The elongator complex catalyzes formation of carboxymethyluridine in the wobble base at position 34 in tRNAs.
      
 0.596
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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