Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
cand1Cullin-associated and neddylation-dissociated 1. (1230 aa)    
Predicted Functional Partners:
cul1a
Cullin 1a; Belongs to the cullin family.
   
 0.985
rbx1
Ring-box 1, E3 ubiquitin protein ligase.
    
 0.982
cul2
Cullin 2; Belongs to the cullin family.
    
 0.970
cul1b
Cullin 1b; Belongs to the cullin family.
   
 
 0.953
UBE2M
Si:ch1073-205c8.3; Belongs to the ubiquitin-conjugating enzyme family.
    
 0.952
cul5a
Cullin 5a; Belongs to the cullin family.
   
 0.951
cul3b
Cullin 3b; Belongs to the cullin family.
   
 0.951
skp1
S-phase kinase-associated protein 1A; Belongs to the SKP1 family.
    
 0.939
nedd8
NEDD8 ubiquitin-like modifier.
    
 0.938
nedd8l
NEDD8 ubiquitin-like modifier, like.
    
 0.938
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
Server load: low (6%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.