STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC101886560Uncharacterized protein; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (520 aa)    
Predicted Functional Partners:
trpm2
Transient receptor potential cation channel subfamily M member 2; Nonselective, voltage-independent cation channel that mediates Ca(2+) influx, leading to increased cytoplasmic Ca(2+) levels. Functions as ligand-gated ion channel. Binding of ADP-ribose to the cytoplasmic N-terminal region causes a conformation change; the channel is primed but still requires Ca(2+) binding to trigger channel opening. Belongs to the transient receptor (TC 1.A.4) family. LTrpC subfamily. TRPM2 sub-subfamily.
      
 0.834
stim1a
Stromal interaction molecule 1a.
      
 0.651
brms1la
Breast cancer metastasis-suppressor 1-like protein-A; Involved in the histone deacetylase (HDAC1)-dependent transcriptional repression activity; Belongs to the BRMS1 family.
      
 0.564
ogdha
Oxoglutarate (alpha-ketoglutarate) dehydrogenase a (lipoamide).
      
 0.563
pgpep1
Pyroglutamyl-peptidase I.
      
 0.561
wscd2
WSC domain-containing protein 2.
      
 0.552
get4
Guided entry of tail-anchored proteins factor 4.
    
   0.540
camk2a
Calcium/calmodulin-dependent protein kinase II alpha; Belongs to the protein kinase superfamily.
      
 0.482
eno2
Eno2 protein.
  
  
 0.461
stim1b
Stromal interaction molecule 1b.
      
 0.460
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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