Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
dusp23aDual-specificity phosphatase 23a. (161 aa)    
Predicted Functional Partners:
exosc8
Exosome component 8.
   
   0.749
espl1
Extra spindle pole bodies-like 1, separase.
   
 0.713
cdc6
Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family.
   
 
 0.685
nrde2
NRDE-2, necessary for RNA interference, domain-containing.
    
 
 0.646
stk38a
Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.
   
 0.585
stk38b
Serine/threonine kinase 38b; Belongs to the protein kinase superfamily.
   
 0.585
stk38l
Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.
   
 0.585
fzr1a
Fizzy/cell division cycle 20 related 1 (Drosophila).
   
 0.568
intu
Protein inturned; Plays a key role in ciliogenesis and embryonic development. Regulator of cilia formation by controlling the organization of the apical actin cytoskeleton and the positioning of the basal bodies at the apical cell surface, which in turn is essential for the normal orientation of elongating ciliary microtubules. Plays a key role in definition of cell polarity via its role in ciliogenesis but not via conversion extension. Has an indirect effect on hedgehog signaling (By similarity); Belongs to the inturned family.
   
 0.568
fzr1b
Fizzy/cell division cycle 20-related 1b.
   
 0.568
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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