Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-expression
Experiments
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[Homology]
Score
casq1bCalsequestrin; Calsequestrin is a high-capacity, moderate affinity, calcium- binding protein and thus acts as an internal calcium store in muscle. (454 aa)    
Predicted Functional Partners:
trdn
Triadin.
   
 0.995
Trdn
Si:ch211-199i15.5.
   
 0.989
asph
Aspartate beta-hydroxylase.
    
 0.984
ryr1a
Ryanodine receptor 1a (skeletal).
   
 0.942
RYR2
Uncharacterized protein.
   
 0.941
unm_hu7910
Un-named hu7910.
   
 0.929
ryr2b
Ryanodine receptor 2b (cardiac).
   
 0.910
casq2
Calsequestrin; Calsequestrin is a high-capacity, moderate affinity, calcium- binding protein and thus acts as an internal calcium store in muscle.
  
 
0.887
ryr3
Ryanodine receptor 3.
   
 0.861
atp2a1
Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium.
   
 
 0.843
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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