Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
saal1Protein saal1; Plays a role in promoting cell proliferation in response to proinflammatory stimuli; Belongs to the SAAL1 family. (469 aa)    
Predicted Functional Partners:
ano9b
Anoctamin.
      
 0.811
TMEM19
Transmembrane protein 19.
      
 0.799
caps2
Calcyphosine 2.
      
 0.790
sergef
Secretion-regulating guanine nucleotide exchange factor.
 
    
 0.781
pkp3b
Plakophilin 3b.
      
 0.775
fibina
Fin bud initiation factor a.
      
 0.735
gtf2h1
General transcription factor IIH, polypeptide 1.
      
 0.720
swap70b
Switching B cell complex subunit SWAP70b.
      
 0.718
gnb5a
Guanine nucleotide-binding protein subunit beta-5a; Enhances GTPase-activating protein (GAP) activity of regulator of G protein signaling (RGS) proteins, hence involved in the termination of the signaling initiated by the G protein coupled receptors (GPCRs) by accelerating the GTP hydrolysis on the G-alpha subunits, thereby promoting their inactivation (Probable). Increases RGS9 GTPase-activating protein (GAP) activity, hence contributes to the deactivation of G protein signaling initiated by D(2) dopamine receptors (By similarity). Along with gnb5b, plays an important role in neuronal [...]
      
 0.683
tgm2b
Transglutaminase 2b.
      
 0.669
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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