Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Neighborhood
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Co-occurrence
Co-expression
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[Homology]
Score
ptbp1aPolypyrimidine tract-binding protein 1a. (574 aa)    
Predicted Functional Partners:
hnrnpk
Heterogeneous nuclear ribonucleoprotein K.
   
 
 0.891
elavl1a
ELAV-like protein; Belongs to the RRM elav family.
   
 
 0.780
srrm4
Serine/arginine repetitive matrix protein 4; Splicing factor specifically required for neural cell differentiation. Acts in conjunction with nPTB/PTBP2 by binding directly to its regulated target transcripts and promotes neural-specific exon inclusion in many genes that function in neural cell differentiation. Required to promote the inclusion of neural- specific exon 10 in nPTB/PTBP2, leading to increased expression of neural-specific nPTB/PTBP2 (By similarity).
      
 0.774
pcbp2
Poly(rC)-binding protein 2.
   
 0.764
rbfox2
RNA-binding fox-1 homolog 2.
    
 
 0.761
hnrnpa1b
Heterogeneous nuclear ribonucleoprotein A1b.
    
 
 0.744
hnrnpl
Heterogeneous nuclear ribonucleoprotein L.
   
0.740
hnrpkl
Heterogeneous nuclear ribonucleoprotein K,-like.
   
 0.733
rbm10
RNA-binding motif protein 10.
    
 0.722
hnrnph1
Heterogeneous nuclear ribonucleoprotein H1.
   
 0.716
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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