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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ptbp1aPolypyrimidine tract-binding protein 1a. (574 aa)    
Predicted Functional Partners:
hnrnpk
Heterogeneous nuclear ribonucleoprotein K.
   
 
 0.951
hnrnpa1b
Heterogeneous nuclear ribonucleoprotein A1b.
   
 0.822
tra2b
Transformer 2 beta homolog.
   
 0.772
srrm4
Serine/arginine repetitive matrix protein 4; Splicing factor specifically required for neural cell differentiation. Acts in conjunction with nPTB/PTBP2 by binding directly to its regulated target transcripts and promotes neural-specific exon inclusion in many genes that function in neural cell differentiation. Required to promote the inclusion of neural- specific exon 10 in nPTB/PTBP2, leading to increased expression of neural-specific nPTB/PTBP2 (By similarity).
      
 0.766
hnrnpub
Heterogeneous nuclear ribonucleoprotein Ub.
   
 0.763
pcbp2
Poly(rC)-binding protein 2.
   
 0.757
fus
FUS RNA-binding protein.
   
 0.753
rest
RE1-silencing transcription factor; Transcriptional repressor which binds neuron-restrictive silencer element (NRSE) and represses neuronal gene transcription in non-neuronal cells.
   
  
 0.747
hnrnpc
Heterogeneous nuclear ribonucleoprotein C.
   
 
 0.736
srsf2a
Serine and arginine-rich-splicing factor 2a.
   
 0.720
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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