| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| aldh18a1 | aldh4a1 | ENSDARP00000137162 | ENSDARP00000142254 | Delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family. | Delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial; Irreversible conversion of delta-1-pyrroline-5-carboxylate (P5C), derived either from proline or ornithine, to glutamate. This is a necessary step in the pathway interconnecting the urea and tricarboxylic acid cycles (By similarity); Belongs to the aldehyde dehydrogenase family. | 0.992 |
| aldh18a1 | p4ha2 | ENSDARP00000137162 | ENSDARP00000143396 | Delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family. | Procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), alpha polypeptide 2. | 0.454 |
| aldh18a1 | prodha | ENSDARP00000137162 | ENSDARP00000085764 | Delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family. | Proline dehydrogenase; Converts proline to delta-1-pyrroline-5-carboxylate. | 0.952 |
| aldh18a1 | pycr1a | ENSDARP00000137162 | ENSDARP00000133333 | Delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family. | Pyrroline-5-carboxylate reductase; Belongs to the pyrroline-5-carboxylate reductase family. | 0.959 |
| aldh18a1 | pycr1b | ENSDARP00000137162 | ENSDARP00000142190 | Delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family. | Pyrroline-5-carboxylate reductase; Belongs to the pyrroline-5-carboxylate reductase family. | 0.951 |
| aldh18a1 | pycr3 | ENSDARP00000137162 | ENSDARP00000011713 | Delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family. | Pyrroline-5-carboxylate reductase 3; Enzyme that catalyzes the last step in proline biosynthesis. Proline is synthesized from either glutamate or ornithine; both are converted to pyrroline-5-carboxylate (P5C), and then to proline via pyrroline-5-carboxylate reductases (PYCRs). PYCRL is exclusively linked to the conversion of ornithine to proline. | 0.959 |
| aldh18a1 | zgc:92040 | ENSDARP00000137162 | ENSDARP00000118592 | Delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family. | Proline dehydrogenase; Converts proline to delta-1-pyrroline-5-carboxylate. | 0.952 |
| aldh4a1 | aldh18a1 | ENSDARP00000142254 | ENSDARP00000137162 | Delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial; Irreversible conversion of delta-1-pyrroline-5-carboxylate (P5C), derived either from proline or ornithine, to glutamate. This is a necessary step in the pathway interconnecting the urea and tricarboxylic acid cycles (By similarity); Belongs to the aldehyde dehydrogenase family. | Delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family. | 0.992 |
| aldh4a1 | prodha | ENSDARP00000142254 | ENSDARP00000085764 | Delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial; Irreversible conversion of delta-1-pyrroline-5-carboxylate (P5C), derived either from proline or ornithine, to glutamate. This is a necessary step in the pathway interconnecting the urea and tricarboxylic acid cycles (By similarity); Belongs to the aldehyde dehydrogenase family. | Proline dehydrogenase; Converts proline to delta-1-pyrroline-5-carboxylate. | 0.942 |
| aldh4a1 | pycr1a | ENSDARP00000142254 | ENSDARP00000133333 | Delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial; Irreversible conversion of delta-1-pyrroline-5-carboxylate (P5C), derived either from proline or ornithine, to glutamate. This is a necessary step in the pathway interconnecting the urea and tricarboxylic acid cycles (By similarity); Belongs to the aldehyde dehydrogenase family. | Pyrroline-5-carboxylate reductase; Belongs to the pyrroline-5-carboxylate reductase family. | 0.922 |
| aldh4a1 | pycr1b | ENSDARP00000142254 | ENSDARP00000142190 | Delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial; Irreversible conversion of delta-1-pyrroline-5-carboxylate (P5C), derived either from proline or ornithine, to glutamate. This is a necessary step in the pathway interconnecting the urea and tricarboxylic acid cycles (By similarity); Belongs to the aldehyde dehydrogenase family. | Pyrroline-5-carboxylate reductase; Belongs to the pyrroline-5-carboxylate reductase family. | 0.964 |
| aldh4a1 | pycr3 | ENSDARP00000142254 | ENSDARP00000011713 | Delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial; Irreversible conversion of delta-1-pyrroline-5-carboxylate (P5C), derived either from proline or ornithine, to glutamate. This is a necessary step in the pathway interconnecting the urea and tricarboxylic acid cycles (By similarity); Belongs to the aldehyde dehydrogenase family. | Pyrroline-5-carboxylate reductase 3; Enzyme that catalyzes the last step in proline biosynthesis. Proline is synthesized from either glutamate or ornithine; both are converted to pyrroline-5-carboxylate (P5C), and then to proline via pyrroline-5-carboxylate reductases (PYCRs). PYCRL is exclusively linked to the conversion of ornithine to proline. | 0.969 |
| aldh4a1 | zgc:92040 | ENSDARP00000142254 | ENSDARP00000118592 | Delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial; Irreversible conversion of delta-1-pyrroline-5-carboxylate (P5C), derived either from proline or ornithine, to glutamate. This is a necessary step in the pathway interconnecting the urea and tricarboxylic acid cycles (By similarity); Belongs to the aldehyde dehydrogenase family. | Proline dehydrogenase; Converts proline to delta-1-pyrroline-5-carboxylate. | 0.990 |
| lap3 | p4ha1a | ENSDARP00000083458 | ENSDARP00000105672 | Leucine aminopeptidase 3. | Prolyl 4-hydroxylase, alpha polypeptide I a. | 0.950 |
| lap3 | p4ha2 | ENSDARP00000083458 | ENSDARP00000143396 | Leucine aminopeptidase 3. | Procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), alpha polypeptide 2. | 0.944 |
| lap3 | p4ha3 | ENSDARP00000083458 | ENSDARP00000141707 | Leucine aminopeptidase 3. | Prolyl 4-hydroxylase, alpha polypeptide III. | 0.936 |
| lap3 | prodha | ENSDARP00000083458 | ENSDARP00000085764 | Leucine aminopeptidase 3. | Proline dehydrogenase; Converts proline to delta-1-pyrroline-5-carboxylate. | 0.945 |
| lap3 | pycr1a | ENSDARP00000083458 | ENSDARP00000133333 | Leucine aminopeptidase 3. | Pyrroline-5-carboxylate reductase; Belongs to the pyrroline-5-carboxylate reductase family. | 0.886 |
| lap3 | pycr1b | ENSDARP00000083458 | ENSDARP00000142190 | Leucine aminopeptidase 3. | Pyrroline-5-carboxylate reductase; Belongs to the pyrroline-5-carboxylate reductase family. | 0.886 |
| lap3 | pycr3 | ENSDARP00000083458 | ENSDARP00000011713 | Leucine aminopeptidase 3. | Pyrroline-5-carboxylate reductase 3; Enzyme that catalyzes the last step in proline biosynthesis. Proline is synthesized from either glutamate or ornithine; both are converted to pyrroline-5-carboxylate (P5C), and then to proline via pyrroline-5-carboxylate reductases (PYCRs). PYCRL is exclusively linked to the conversion of ornithine to proline. | 0.963 |