Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
rab4aRas-related protein Rab-4A; Protein transport. Probably involved in vesicular traffic (By similarity); Belongs to the small GTPase superfamily. Rab family. (213 aa)    
Predicted Functional Partners:
rbsn
Rabenosyn, RAB effector.
    
 0.990
rufy1
RUN and FYVE domain-containing 1.
    
 0.987
rufy2
RUN and FYVE domain-containing 2.
    
 0.952
tbc1d16
TBC1 domain family, member 16.
    
 0.838
rabep1
Rabaptin, RAB GTPase-binding effector protein 1.
    
 
 0.819
chm
Rab proteins geranylgeranyltransferase component A; Substrate-binding subunit (component A) of the Rab geranylgeranyltransferase (GGTase) complex. Binds unprenylated Rab proteins and presents the substrate peptide to the catalytic component B. The component A is thought to be regenerated by transferring its prenylated Rab back to the donor membrane.
    
 0.738
hgs
Hepatocyte growth factor-regulated tyrosine kinase substrate.
    
 
 0.686
stam
Signal transducing adaptor molecule (SH3 domain and ITAM motif) 1.
    
 0.666
rabep2
Rabaptin, RAB GTPase-binding effector protein 2.
    
 
 0.656
rufy3
RUN and FYVE domain-containing 3.
    
  0.655
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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