STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cyp2k22Cytochrome P450, family 2, subfamily K, polypeptide 22; Belongs to the cytochrome P450 family. (503 aa)    
Predicted Functional Partners:
sult2st3
Sulfotransferase; Belongs to the sulfotransferase 1 family.
      
 0.974
slco1f4
Solute carrier organic anion transporter family member.
   
  
 0.900
fdx1b
Ferredoxin 1b.
  
 0.724
fkbp5
Peptidylprolyl isomerase.
      
 0.672
sult1st2
Cytosolic sulfotransferase 2; Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the sulfate conjugation of a variety of xenobiotic and endogenous compounds, including 2-naphthol, hydroxychlorobiphenyls, T3 (triiodo-L-thyronine), T4 (thyroxine), estrone and DOPA.
   
  
 0.664
fdx1
Ferredoxin 1.
  
 0.647
apoa4b.2
Apolipoprotein A-IV b, tandem duplicate 2.
   
  
 0.625
aasdh
Beta-alanine-activating enzyme; Covalently binds beta-alanine in an ATP-dependent manner to form a thioester bond with its phosphopantetheine group and transfers it to an, as yet, unknown acceptor. May be required for a post- translational protein modification or for post-transcriptional modification of an RNA.
  
 0.561
cyp8b3
Cytochrome P450, family 8, subfamily B, polypeptide 3.
   
  
 0.558
apoa4b.3
Apolipoprotein A-IV b, tandem duplicate 2.
   
  
 0.550
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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