STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ptgesMicrosomal prostaglandin E synthase 1. (146 aa)    
Predicted Functional Partners:
ptges3a
Prostaglandin E synthase 3a (cytosolic).
   
 
 0.981
ptgs2a
Prostaglandin-endoperoxide synthase 2a.
   
 
 0.977
ptgs1
Prostaglandin-endoperoxide synthase 1.
   
 
 0.976
ptgs2b
Prostaglandin-endoperoxide synthase 2b.
   
 
 0.963
ptgesl
Prostaglandin E synthase 2; Isomerase that catalyzes the conversion of PGH2 into the more stable prostaglandin E2 (PGE2); Belongs to the GST superfamily.
     
 0.962
ptgdsb.1
Lipocalin-type prostaglandin D synthase-like protein; Belongs to the calycin superfamily. Lipocalin family.
   
 
 0.956
prxl2b
Prostamide/prostaglandin F synthase; Catalyzes the reduction of prostaglandin-ethanolamide H(2) (prostamide H(2)) to prostamide F(2alpha) with NADPH as proton donor. Also able to reduce prostaglandin H(2) to prostaglandin F(2alpha) (By similarity); Belongs to the peroxiredoxin-like PRXL2 family. Prostamide/prostaglandin F synthase subfamily.
     
 0.928
tbxas1
Thromboxane A synthase 1 (platelet); Belongs to the cytochrome P450 family.
     
 0.927
ptgdsb.2
Prostaglandin D2 synthase b, tandem duplicate 2; Belongs to the calycin superfamily. Lipocalin family.
   
 
 0.926
cbr1l
Carbonyl reductase 1-like; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
   
 
 0.922
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
Server load: medium (68%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.