Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ptgesMicrosomal prostaglandin E synthase 1. (146 aa)    
Predicted Functional Partners:
ptges3a
Prostaglandin E synthase 3a (cytosolic).
   
 
 0.991
ptgesl
Prostaglandin E synthase 2; Isomerase that catalyzes the conversion of PGH2 into the more stable prostaglandin E2 (PGE2); Belongs to the GST superfamily.
     
 0.990
ptgs1
Prostaglandin-endoperoxide synthase 1.
     
 0.982
ptgs2a
Prostaglandin-endoperoxide synthase 2a.
     
 0.973
hpgd
15-hydroxyprostaglandin dehydrogenase; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
     
 0.971
ptgdsb.1
Lipocalin-type prostaglandin D synthase-like protein; Belongs to the calycin superfamily. Lipocalin family.
   
 
 0.969
tbxas1
Thromboxane A synthase 1 (platelet); Belongs to the cytochrome P450 family.
     
 0.968
prxl2b
Prostamide/prostaglandin F synthase; Catalyzes the reduction of prostaglandin-ethanolamide H(2) (prostamide H(2)) to prostamide F(2alpha) with NADPH as proton donor. Also able to reduce prostaglandin H(2) to prostaglandin F(2alpha) (By similarity); Belongs to the peroxiredoxin-like PRXL2 family. Prostamide/prostaglandin F synthase subfamily.
     
 0.965
ptgs2b
Prostaglandin-endoperoxide synthase 2b.
   
 
 0.960
ptgdsa
Prostaglandin D2 synthase a; Belongs to the calycin superfamily. Lipocalin family.
     
 0.960
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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