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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
tnxbaTenascin XBa. (1594 aa)    
Predicted Functional Partners:
dstyk
Dual serine/threonine and tyrosine protein kinase; May act as a positive regulator of ERK phosphorylation downstream of fibroblast growth factor-receptor activation. May induce both caspase-dependent apoptosis and caspase-independent cell death (By similarity). Plays a role in the embryonic development.
      
 0.745
fkbp14
Peptidylprolyl isomerase.
      
 0.669
plod1a
Procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1a.
      
 0.669
b4galt7
Xylosylprotein beta 1,4-galactosyltransferase, polypeptide 7 (galactosyltransferase I).
      
 0.646
pdxkb
Novel protein similar to vertebrate pyridoxal (Pyridoxine, vitamin B6) kinase (PDXK).
      
 0.620
hpse2
Heparanase 2.
      
 0.582
lrig2
Leucine-rich repeats and immunoglobulin-like domains 2.
      
 0.582
fkbpl
FKBP prolyl isomerase-like.
      
 0.569
adamts2
ADAM metallopeptidase with thrombospondin type 1 motif, 2.
      
 0.568
col5a1
Procollagen, type V, alpha 1.
   
  
 0.484
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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