mylipa protein (Danio rerio) - STRING interaction network

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mylipa

E3 ubiquitin-protein ligase MYLIP-A; E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of myosin regulatory light chain (MRLC) (By similarity). Regulates cell movements during gastrulation by acting downstream of fz7 to antagonize the frizzled-signaling pathway. (472 aa)

Predicted Functional Partners:

vldlr

0.848

lrp8

0.843

ldlra

0.819

ldlrb

0.819

mtus1a

0.797

cnpy2

0.778

stmnd1

0.740

ccnb2

0.700

cnpy1

0.665

tatdn2

0.647

Your Current Organism:

Danio rerio

NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ccnb2	mylipa	ENSDARP00000052540	ENSDARP00000012386	Cyclin B2; Belongs to the cyclin family.	E3 ubiquitin-protein ligase MYLIP-A; E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of myosin regulatory light chain (MRLC) (By similarity). Regulates cell movements during gastrulation by acting downstream of fz7 to antagonize the frizzled-signaling pathway.	0.700
ccnb2	tatdn2	ENSDARP00000052540	ENSDARP00000094655	Cyclin B2; Belongs to the cyclin family.	TatD DNase domain-containing 2.	0.751
cnpy1	mylipa	ENSDARP00000009432	ENSDARP00000012386	Protein canopy-1; Involved in the maintenance of the midbrain-hindbrain boundary (MHB) organizer. Contributes to a positive-feedback loop of FGF signaling in the MHB, enabling the MHB to exert its role as an organizer for the tectal and cerebellar development.	E3 ubiquitin-protein ligase MYLIP-A; E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of myosin regulatory light chain (MRLC) (By similarity). Regulates cell movements during gastrulation by acting downstream of fz7 to antagonize the frizzled-signaling pathway.	0.665
cnpy2	mylipa	ENSDARP00000149703	ENSDARP00000012386	Canopy FGF-signaling regulator 2.	E3 ubiquitin-protein ligase MYLIP-A; E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of myosin regulatory light chain (MRLC) (By similarity). Regulates cell movements during gastrulation by acting downstream of fz7 to antagonize the frizzled-signaling pathway.	0.778
ldlra	ldlrb	ENSDARP00000046296	ENSDARP00000126428	Low density lipoprotein receptor a.	Low density lipoprotein receptor b.	0.934
ldlra	mylipa	ENSDARP00000046296	ENSDARP00000012386	Low density lipoprotein receptor a.	E3 ubiquitin-protein ligase MYLIP-A; E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of myosin regulatory light chain (MRLC) (By similarity). Regulates cell movements during gastrulation by acting downstream of fz7 to antagonize the frizzled-signaling pathway.	0.819
ldlrb	ldlra	ENSDARP00000126428	ENSDARP00000046296	Low density lipoprotein receptor b.	Low density lipoprotein receptor a.	0.934
ldlrb	mylipa	ENSDARP00000126428	ENSDARP00000012386	Low density lipoprotein receptor b.	E3 ubiquitin-protein ligase MYLIP-A; E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of myosin regulatory light chain (MRLC) (By similarity). Regulates cell movements during gastrulation by acting downstream of fz7 to antagonize the frizzled-signaling pathway.	0.819
lrp8	mylipa	ENSDARP00000143584	ENSDARP00000012386	Low density lipoprotein receptor-related protein 8, apolipoprotein e receptor.	E3 ubiquitin-protein ligase MYLIP-A; E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of myosin regulatory light chain (MRLC) (By similarity). Regulates cell movements during gastrulation by acting downstream of fz7 to antagonize the frizzled-signaling pathway.	0.843
mtus1a	mylipa	ENSDARP00000096667	ENSDARP00000012386	Microtubule-associated tumor suppressor 1 homolog A; May inhibit cell proliferation.	E3 ubiquitin-protein ligase MYLIP-A; E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of myosin regulatory light chain (MRLC) (By similarity). Regulates cell movements during gastrulation by acting downstream of fz7 to antagonize the frizzled-signaling pathway.	0.797
mylipa	ccnb2	ENSDARP00000012386	ENSDARP00000052540	E3 ubiquitin-protein ligase MYLIP-A; E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of myosin regulatory light chain (MRLC) (By similarity). Regulates cell movements during gastrulation by acting downstream of fz7 to antagonize the frizzled-signaling pathway.	Cyclin B2; Belongs to the cyclin family.	0.700
mylipa	cnpy1	ENSDARP00000012386	ENSDARP00000009432	E3 ubiquitin-protein ligase MYLIP-A; E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of myosin regulatory light chain (MRLC) (By similarity). Regulates cell movements during gastrulation by acting downstream of fz7 to antagonize the frizzled-signaling pathway.	Protein canopy-1; Involved in the maintenance of the midbrain-hindbrain boundary (MHB) organizer. Contributes to a positive-feedback loop of FGF signaling in the MHB, enabling the MHB to exert its role as an organizer for the tectal and cerebellar development.	0.665
mylipa	cnpy2	ENSDARP00000012386	ENSDARP00000149703	E3 ubiquitin-protein ligase MYLIP-A; E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of myosin regulatory light chain (MRLC) (By similarity). Regulates cell movements during gastrulation by acting downstream of fz7 to antagonize the frizzled-signaling pathway.	Canopy FGF-signaling regulator 2.	0.778
mylipa	ldlra	ENSDARP00000012386	ENSDARP00000046296	E3 ubiquitin-protein ligase MYLIP-A; E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of myosin regulatory light chain (MRLC) (By similarity). Regulates cell movements during gastrulation by acting downstream of fz7 to antagonize the frizzled-signaling pathway.	Low density lipoprotein receptor a.	0.819
mylipa	ldlrb	ENSDARP00000012386	ENSDARP00000126428	E3 ubiquitin-protein ligase MYLIP-A; E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of myosin regulatory light chain (MRLC) (By similarity). Regulates cell movements during gastrulation by acting downstream of fz7 to antagonize the frizzled-signaling pathway.	Low density lipoprotein receptor b.	0.819
mylipa	lrp8	ENSDARP00000012386	ENSDARP00000143584	E3 ubiquitin-protein ligase MYLIP-A; E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of myosin regulatory light chain (MRLC) (By similarity). Regulates cell movements during gastrulation by acting downstream of fz7 to antagonize the frizzled-signaling pathway.	Low density lipoprotein receptor-related protein 8, apolipoprotein e receptor.	0.843
mylipa	mtus1a	ENSDARP00000012386	ENSDARP00000096667	E3 ubiquitin-protein ligase MYLIP-A; E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of myosin regulatory light chain (MRLC) (By similarity). Regulates cell movements during gastrulation by acting downstream of fz7 to antagonize the frizzled-signaling pathway.	Microtubule-associated tumor suppressor 1 homolog A; May inhibit cell proliferation.	0.797
mylipa	stmnd1	ENSDARP00000012386	ENSDARP00000135200	E3 ubiquitin-protein ligase MYLIP-A; E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of myosin regulatory light chain (MRLC) (By similarity). Regulates cell movements during gastrulation by acting downstream of fz7 to antagonize the frizzled-signaling pathway.	Stathmin domain-containing 1.	0.740
mylipa	tatdn2	ENSDARP00000012386	ENSDARP00000094655	E3 ubiquitin-protein ligase MYLIP-A; E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of myosin regulatory light chain (MRLC) (By similarity). Regulates cell movements during gastrulation by acting downstream of fz7 to antagonize the frizzled-signaling pathway.	TatD DNase domain-containing 2.	0.647
mylipa	vldlr	ENSDARP00000012386	ENSDARP00000020206	E3 ubiquitin-protein ligase MYLIP-A; E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of myosin regulatory light chain (MRLC) (By similarity). Regulates cell movements during gastrulation by acting downstream of fz7 to antagonize the frizzled-signaling pathway.	Very low density lipoprotein receptor.	0.848

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