Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
mmp13aMatrix metallopeptidase 13a. (476 aa)    
Predicted Functional Partners:
bsg
Basigin.
   
 
  0.900
mmp2
Matrix metalloproteinase 2.
  
0.887
timp2b
TIMP metallopeptidase inhibitor 2b.
    
 0.837
mmp20b
Matrix metallopeptidase 20b (enamelysin).
  
 
0.673
mmp30
Matrix metallopeptidase 30.
  
 
0.664
tnfaip2b
Tumor necrosis factor, alpha-induced protein 2b.
      
 0.660
ube2v1
Ubiquitin-conjugating enzyme E2 variant 1.
     
  0.628
irg1l
Immunoresponsive gene 1,-like.
     
 0.601
cxcl18b
Chemokine (C-X-C motif) ligand 18b.
      
 0.596
hbegfa
Heparin-binding EGF-like growth factor a.
    
 0.577
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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