Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
glra3Glycine receptor, alpha 3; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (450 aa)    
Predicted Functional Partners:
gphnb
Gephyrin2 isoform.
    
 
 0.867
gphna
Gephyrin a.
    
 
 0.867
glra2
Glycine receptor, alpha 2; Belongs to the ligand-gated ion channel (TC 1.A.9) family.
     
  0.866
glrbb
Glycine receptor beta subunit 2; Belongs to the ligand-gated ion channel (TC 1.A.9) family.
  
0.853
glrba
Glycine receptor betaZ subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family.
  
0.847
glra1
Glycine receptor subunit alphaZ1; Glycine receptors are ligand-gated chloride channels. Channel opening is triggered by extracellular glycine. Plays an important role in the down-regulation of neuronal excitability. Contributes to the generation of inhibitory postsynaptic currents. Channel activity is potentiated by ethanol (By similarity); Belongs to the ligand-gated ion channel (TC 1.A.9) family. Glycine receptor (TC 1.A.9.3) subfamily. GLRA1 sub-subfamily.
     
  0.830
slc6a9
Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
      
 0.719
grin2ab
Glutamate receptor, ionotropic, N-methyl D-aspartate 2A, b.
   
  
 0.600
cnksr3
Cnksr family member 3.
      
 0.583
gria3a
Glutamate receptor, ionotropic, AMPA 3a.
   
 
 0.566
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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