Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
tha1Threonine aldolase 1. (413 aa)    
Predicted Functional Partners:
shmt2
Serine hydroxymethyltransferase 2 (mitochondrial).
   
 0.990
gcat
Glycine C-acetyltransferase.
  
 
 0.981
F1QDE0_DANRE
Si:ch1073-100f3.2; Belongs to the mitochondrial carrier (TC 2.A.29) family.
      
 0.981
ENSDARP00000134442
PALP domain-containing protein.
  
 
 0.979
sdsl
Serine dehydratase-like.
  
 
 0.978
shmt1
Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family.
   
 0.977
gldc
Glycine dehydrogenase (decarboxylating).
    
 0.974
alas2
5-aminolevulinate synthase, erythroid-specific, mitochondrial; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
  
 
 0.973
agxtb
Serine--pyruvate aminotransferase.
    
 0.971
tdh
L-threonine dehydrogenase.
    
 0.971
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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