Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
il17dInterleukin 17_4. (212 aa)    
Predicted Functional Partners:
wu:fl23c11
SEFIR domain-containing protein.
    
 0.771
il17rc
Interleukin 17 receptor C.
     
 0.679
il15
Interleukin; Belongs to the IL-15/IL-21 family.
      
 0.594
il17rd
Interleukin-17 receptor D; Feedback inhibitor of fibroblast growth factor mediated Ras- MAPK signaling and ERK activation. May inhibit FGF-induced FGFR1 tyrosine phosphorylation.
    
 0.581
il17a/f2
Interleukin 17a/f2.
      
 0.560
il6
Interleukin 6 (interferon, beta 2).
      
 0.558
il26
Interleukin 26.
      
 0.554
il16
Interleukin 16.
      
 0.489
il22
Interleukin 22.
   
  
 0.473
il17ra1a
Interleukin 17 receptor A1a.
    
 0.466
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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