Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
pahPhenylalanine hydroxylase. (449 aa)    
Predicted Functional Partners:
spra
Sepiapterin reductase a.
   
 
 0.988
tat
Tyrosine aminotransferase; Transaminase involved in tyrosine breakdown. Converts tyrosine to p-hydroxyphenylpyruvate.
   
 
 0.988
pcbd1
Pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha.
  
 0.986
sprb
Sepiapterin reductase b.
   
 
 0.983
ddc
Dopa decarboxylase.
   
 0.978
qdpra
Quinoid dihydropteridine reductase a.
   
 0.975
got2a
Aspartate aminotransferase.
  
 
 0.966
got1
Aspartate aminotransferase.
  
 
 0.964
dhfr
Dihydrofolate reductase.
     
 0.961
tyr
Tyrosinase.
     
 0.954
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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