Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
ctnnal1Catenin (cadherin-associated protein), alpha-like 1. (754 aa)    
Predicted Functional Partners:
afdna
Afadin, adherens junction formation factor a.
   
 0.803
sntg2
Syntrophin, gamma 2.
   
 
 0.766
sntg1
Syntrophin, gamma 1.
   
 
 0.766
abitram
Protein Abitram; May regulate actin polymerization, filopodia dynamics and arborization of neurons; Belongs to the ABITRAM family.
      
 0.740
zgc:91910
Zgc:91910.
      
 0.734
wdyhv1
Protein N-terminal glutamine amidohydrolase; Mediates the side-chain deamidation of N-terminal glutamine residues to glutamate, an important step in N-end rule pathway of protein degradation. Conversion of the resulting N-terminal glutamine to glutamate renders the protein susceptible to arginylation, polyubiquitination and degradation as specified by the N-end rule. Does not act on substrates with internal or C-terminal glutamine and does not act on non-glutamine residues in any position. Does not deaminate acetylated N-terminal glutamine. With the exception of proline, all tested sec [...]
      
 0.734
si:rp71-45k5.2
Si:rp71-45k5.2.
      
 0.734
sntb2
Syntrophin, beta 2.
    
 
 0.712
sntb1
Syntrophin, basic 1.
    
 
 0.712
SNTA1
Syntrophin alpha 1.
    
 
 0.712
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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