Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
arglu1aArginine and glutamate-rich protein 1-A; Belongs to the UPF0430 family. (251 aa)    
Predicted Functional Partners:
snrnp70
Small nuclear ribonucleoprotein 70 (U1).
   
 
 0.770
ncbp2
Nuclear cap-binding protein subunit 2; Component of the cap-binding complex (CBC), which binds co- transcriptionally to the 5' cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing, translation regulation, nonsense- mediated mRNA decay, RNA-mediated gene silencing (RNAi) by microRNAs (miRNAs) and mRNA export. The CBC complex is involved in mRNA export from the nucleus, leading to the recruitment of the mRNA export machinery to the 5' end of mRNA and to mRNA export in a 5' to 3' direction through the nuclear pore. The CBC complex is also involved in mediating U [...]
    
 
 0.750
pnisr
PNN-interacting serine/arginine-rich protein.
   
  0.738
n4bp2l2
NEDD4-binding protein 2-like 2.
   
 
 0.704
srsf11
Serine and arginine-rich-splicing factor 11.
   
 
 0.672
luc7l3
LUC7-like 3 pre-mRNA-splicing factor.
   
 
 0.663
NDUFAF8
Si:dkey-21c1.6.
      
 0.656
puf60a
Poly-U-binding-splicing factor a.
   
   0.648
puf60b
Poly(U)-binding-splicing factor PUF60-B; DNA- and RNA-binding protein, involved in transcription repression and pre-mRNA splicing.
   
   0.648
pnn
Pinin, desmosome-associated protein.
   
   0.647
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
Server load: low (30%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.