Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
mbipMAP3K12-binding inhibitory protein 1. (361 aa)    
Predicted Functional Partners:
dr1
Down-regulator of transcription 1.
    
 
 0.981
sgf29
SAGA complex-associated factor 29.
    
 
 0.980
tada3l
Transcriptional adapter 3; Functions as a component of the PCAF complex. The PCAF complex is capable of efficiently acetylating histones in a nucleosomal context (By similarity); Belongs to the NGG1 family.
    
 
 0.980
tada2a
Transcriptional adapter.
    
 
 0.980
kat14
Lysine acetyltransferase 14.
    
 
 0.974
zzz3
Zinc finger, ZZ-type-containing 3.
    
 
 0.972
yeats2-2
YEATS domain-containing 2.
   
 
 0.958
yeats2
YEATS domain-containing 2.
   
 
 0.958
wdr5
WD repeat domain 5.
    
 
 0.937
tprkb
EKC/KEOPS complex subunit TPRKB; Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. Tprkb acts as an allosteric effector that regulates the t(6)A activity of the complex. Belongs to the CGI121/TPRKB family.
    
   0.927
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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