STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
dbx1bHomeobox protein DBX1-B; Belongs to the H2.0 homeobox family. (322 aa)    
Predicted Functional Partners:
kctd12.2
Potassium channel tetramerisation domain-containing 12.2.
      
 0.668
kctd12.1
Potassium channel tetramerisation domain-containing 12.1.
      
 0.644
SYNDIG1
Synapse differentiation inducing 1.
   
  
 0.621
slc17a6b
Vesicular glutamate transporter 2.1; Mediates the uptake of glutamate into synaptic vesicles at presynaptic nerve terminals of excitatory neural cells. Required for glutamate release by retinotectal synapses and visual acuity.
      
 0.585
gtf2h3
General transcription factor IIH, polypeptide 3.
      
 0.576
zgc:113210
Zgc:113210.
      
 0.540
neurog1
Neurogenin-1; Transcriptional regulator. Activates transcription by binding to the E box-containing promoter (By similarity). Mediates neuronal differentiation. Required for the development of Rohon-Beard spinal sensory neurons and dorsal root ganglion neurons, but not for primary motoneurons or autonomic neurons. Required for development of all cranial ganglia but not associated glial cells. Regulates epiphysial neurogenesis, acting partially redundantly with ascl1a and downstream of flh. Required for the development of basal forebrain dopaminergic neurons; involved in the specificati [...]
   
  
 0.479
pip4k2aa
Similar to type II phosphatidylinositolphosphate kinase-alpha.
      
 0.473
slc6a5
Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
   
  
 0.471
sox19a
Transcription factor Sox-19a; Transcriptional activator.
   
 
 0.464
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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