Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
LTN1Si:dkey-175g6.5. (1751 aa)    
Predicted Functional Partners:
tcf25
Transcription factor 25 (basic helix-loop-helix).
   
 0.991
LOC108182745
NFACT-R_1 domain-containing protein.
   
 
 0.958
nrxn2b
Neurexin 2b beta.
      
 0.950
znf598
E3 ubiquitin-protein ligase ZNF598; E3 ubiquitin-protein ligase that plays a key role in the ribosome quality control (RQC), a pathway that takes place when a ribosome has stalled during translation. Required for ribosomes to terminally stall during translation of poly(A) sequences by mediating monoubiquitination of a subset of 40S ribosomal subunits. Stalling precludes synthesis of a long poly-lysine tail and initiates the RQC pathway to degrade the potentially detrimental aberrant nascent polypeptide; Belongs to the ZNF598 family.
   
 
 0.930
rpl23a
Ribosomal protein L23a; Belongs to the universal ribosomal protein uL23 family.
    
 0.919
rpl3
Ribosomal protein L3; Belongs to the universal ribosomal protein uL3 family.
    
 0.917
rpl15
Ribosomal protein L15; Belongs to the eukaryotic ribosomal protein eL15 family.
    
 0.888
rpl11
60S ribosomal protein L11; Belongs to the universal ribosomal protein uL5 family.
    
 0.885
rplp0
60S acidic ribosomal protein P0; Ribosomal protein P0 is the functional equivalent of E.coli protein L10; Belongs to the universal ribosomal protein uL10 family.
    
 0.879
rpl26
ATPase H+ transporting V0 subunit e1.
    
 0.879
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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