Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
rabgef1lRAB guanine nucleotide exchange factor (GEF) 1,-like. (470 aa)    
Predicted Functional Partners:
rab5b
RAB5B, member RAS oncogene family.
   
 0.988
rab5c
RAB5C, member RAS oncogene family.
   
 0.973
rab5aa
RAB5A, member RAS oncogene family, a.
   
 0.965
rabep1
Rabaptin, RAB GTPase-binding effector protein 1.
   
 
 0.959
rab24
RAB24, member RAS oncogene family.
   
 0.933
rab5ab
RAB5A, member RAS oncogene family like.
   
 0.927
rab22a
RAB22A, member RAS oncogene family.
   
 0.926
zhx2a
Zinc fingers and homeoboxes 2a.
   
 0.926
rab20
RAB20, member RAS oncogene family.
   
 0.926
rab31
Uncharacterized protein.
   
 0.926
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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