| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| cdc73 | polr2c | ENSDARP00000129750 | ENSDARP00000043811 | Cell division cycle 73, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae). | Polymerase (RNA) II (DNA directed) polypeptide C. | 0.838 |
| cdc73 | polr2gl | ENSDARP00000129750 | ENSDARP00000073018 | Cell division cycle 73, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae). | DNA-directed RNA polymerase II subunit RPB7; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerase II which synthesizes mRNA precursors and many functional non-coding RNAs. Pol II is the central component of the basal RNA polymerase II transcription machinery. It is composed of mobile elements that move relative to each other. RPB7 is part of a subcomplex with RPB4 that binds to a pocket formed by RPB1, RPB2 and RPB6 at the base of the clamp element. The RBP4-RPB7 subcomplex seems [...] | 0.967 |
| cdc73 | polr2h | ENSDARP00000129750 | ENSDARP00000056187 | Cell division cycle 73, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae). | DNA-directed RNA polymerases I, II, and III subunit RPABC3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non- coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively. | 0.970 |
| cdc73 | polr2i | ENSDARP00000129750 | ENSDARP00000059195 | Cell division cycle 73, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae). | DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. | 0.952 |
| cdc73 | polr2j | ENSDARP00000129750 | ENSDARP00000050901 | Cell division cycle 73, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae). | Polymerase (RNA) II (DNA directed) polypeptide J. | 0.907 |
| cdc73 | polr2k | ENSDARP00000129750 | ENSDARP00000099037 | Cell division cycle 73, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae). | Polymerase (RNA) II (DNA directed) polypeptide K. | 0.945 |
| cdc73 | polr2l | ENSDARP00000129750 | ENSDARP00000075655 | Cell division cycle 73, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae). | Polymerase (RNA) II (DNA directed) polypeptide L. | 0.946 |
| cdc73 | supt4h1 | ENSDARP00000129750 | ENSDARP00000147232 | Cell division cycle 73, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae). | Transcription elongation factor SPT4; May function as a component of the DRB sensitivity-inducing factor complex (DSIF complex), which regulates transcription elongation by RNA polymerase II. Probably enhances transcriptional pausing at sites proximal to the promoter, which may facilitate the assembly of an elongation competent RNA polymerase II complex. Also acts to stimulate transcriptional elongation at low nucleotide concentrations. Regulation of transcriptional elongation by this protein is required for the expression of genes which control neuronal development (By similarity). | 0.972 |
| cdc73 | tcea3 | ENSDARP00000129750 | ENSDARP00000013575 | Cell division cycle 73, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae). | Transcription elongation factor A (SII), 3. | 0.845 |
| med31 | polr2c | ENSDARP00000104686 | ENSDARP00000043811 | Mediator of RNA polymerase II transcription subunit 31; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity). | Polymerase (RNA) II (DNA directed) polypeptide C. | 0.870 |
| med31 | polr2gl | ENSDARP00000104686 | ENSDARP00000073018 | Mediator of RNA polymerase II transcription subunit 31; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity). | DNA-directed RNA polymerase II subunit RPB7; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerase II which synthesizes mRNA precursors and many functional non-coding RNAs. Pol II is the central component of the basal RNA polymerase II transcription machinery. It is composed of mobile elements that move relative to each other. RPB7 is part of a subcomplex with RPB4 that binds to a pocket formed by RPB1, RPB2 and RPB6 at the base of the clamp element. The RBP4-RPB7 subcomplex seems [...] | 0.851 |
| med31 | polr2h | ENSDARP00000104686 | ENSDARP00000056187 | Mediator of RNA polymerase II transcription subunit 31; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity). | DNA-directed RNA polymerases I, II, and III subunit RPABC3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non- coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively. | 0.834 |
| med31 | polr2i | ENSDARP00000104686 | ENSDARP00000059195 | Mediator of RNA polymerase II transcription subunit 31; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity). | DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. | 0.840 |
| med31 | polr2j | ENSDARP00000104686 | ENSDARP00000050901 | Mediator of RNA polymerase II transcription subunit 31; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity). | Polymerase (RNA) II (DNA directed) polypeptide J. | 0.892 |
| med31 | polr2k | ENSDARP00000104686 | ENSDARP00000099037 | Mediator of RNA polymerase II transcription subunit 31; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity). | Polymerase (RNA) II (DNA directed) polypeptide K. | 0.813 |
| med31 | polr2l | ENSDARP00000104686 | ENSDARP00000075655 | Mediator of RNA polymerase II transcription subunit 31; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity). | Polymerase (RNA) II (DNA directed) polypeptide L. | 0.824 |
| med31 | tcea3 | ENSDARP00000104686 | ENSDARP00000013575 | Mediator of RNA polymerase II transcription subunit 31; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity). | Transcription elongation factor A (SII), 3. | 0.856 |
| polr2c | cdc73 | ENSDARP00000043811 | ENSDARP00000129750 | Polymerase (RNA) II (DNA directed) polypeptide C. | Cell division cycle 73, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae). | 0.838 |
| polr2c | med31 | ENSDARP00000043811 | ENSDARP00000104686 | Polymerase (RNA) II (DNA directed) polypeptide C. | Mediator of RNA polymerase II transcription subunit 31; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity). | 0.870 |
| polr2c | polr2gl | ENSDARP00000043811 | ENSDARP00000073018 | Polymerase (RNA) II (DNA directed) polypeptide C. | DNA-directed RNA polymerase II subunit RPB7; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerase II which synthesizes mRNA precursors and many functional non-coding RNAs. Pol II is the central component of the basal RNA polymerase II transcription machinery. It is composed of mobile elements that move relative to each other. RPB7 is part of a subcomplex with RPB4 that binds to a pocket formed by RPB1, RPB2 and RPB6 at the base of the clamp element. The RBP4-RPB7 subcomplex seems [...] | 0.999 |
