Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
syt13Synaptotagmin XIII. (420 aa)    
Predicted Functional Partners:
nxph2b
Neurexophilin; May be signaling molecules that resemble neuropeptides.
   
  
 0.727
spata20
Spermatogenesis-associated 20.
      
 0.725
spata18
Mitochondria-eating protein; Key regulator of mitochondrial quality that mediates the repairing or degradation of unhealthy mitochondria in response to mitochondrial damage. Mediator of mitochondrial protein catabolic process (also named MALM) by mediating the degradation of damaged proteins inside mitochondria by promoting the accumulation in the mitochondrial matrix of hydrolases that are characteristic of the lysosomal lumen. Also involved in mitochondrion degradation of damaged mitochondria by promoting the formation of vacuole-like structures (named MIV), which engulf and degrade [...]
      
 0.711
syt16
Synaptotagmin XVI.
      
 0.663
ptn
Pleiotrophin.
      
 0.608
prdm11
PR domain-containing 11.
      
 0.595
lix1
Limb and CNS-expressed 1.
   
  
 0.581
ero1b
Endoplasmic reticulum oxidoreductase beta.
   
  
 0.567
unc13a
Unc-13 homolog A.
      
 0.564
SIPA1
Zmp:0000001168.
      
 0.555
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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