node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
cluap1 | ift172 | ENSDARP00000101015 | ENSDARP00000061333 | Clusterin-associated protein 1 homolog; Required for cilia biogenesis and maintenance in the kidney, the lateral line organ and eye. Appears to function within the multiple intraflagellar transport complex B (IFT-B). Belongs to the CLUAP1 family. | Intraflagellar transport protein 172 homolog; Required for the maintenance and formation of cilia. | 0.993 |
cluap1 | ift20 | ENSDARP00000101015 | ENSDARP00000145296 | Clusterin-associated protein 1 homolog; Required for cilia biogenesis and maintenance in the kidney, the lateral line organ and eye. Appears to function within the multiple intraflagellar transport complex B (IFT-B). Belongs to the CLUAP1 family. | Intraflagellar transport protein 20 homolog; Involved in ciliary process assembly. May play a role in the trafficking of ciliary membrane proteins from the Golgi complex to the cilium. Regulates the platelet-derived growth factor receptor-alpha (PDGFRA) signaling pathway. Plays an important role in spermatogenesis, particularly spermiogenesis, when germ cells form flagella. | 0.924 |
cluap1 | ift46 | ENSDARP00000101015 | ENSDARP00000083038 | Clusterin-associated protein 1 homolog; Required for cilia biogenesis and maintenance in the kidney, the lateral line organ and eye. Appears to function within the multiple intraflagellar transport complex B (IFT-B). Belongs to the CLUAP1 family. | Intraflagellar transport protein 46 homolog; Forms part of a complex involved in intraflagellar transport (IFT), the bi-directional movement of particles required for the assembly, maintenance and functioning of primary cilia. Plays a role in early embryonic development; Belongs to the IFT46 family. | 0.990 |
cluap1 | ift52 | ENSDARP00000101015 | ENSDARP00000066190 | Clusterin-associated protein 1 homolog; Required for cilia biogenesis and maintenance in the kidney, the lateral line organ and eye. Appears to function within the multiple intraflagellar transport complex B (IFT-B). Belongs to the CLUAP1 family. | Intraflagellar transport 52 homolog (Chlamydomonas). | 0.991 |
cluap1 | ift57 | ENSDARP00000101015 | ENSDARP00000013774 | Clusterin-associated protein 1 homolog; Required for cilia biogenesis and maintenance in the kidney, the lateral line organ and eye. Appears to function within the multiple intraflagellar transport complex B (IFT-B). Belongs to the CLUAP1 family. | Intraflagellar transport protein 57 homolog; Required for the formation of cilia. Essential for differentiation and survival of sensory neurons. May also have pro- apoptotic function. | 0.998 |
cluap1 | ift80 | ENSDARP00000101015 | ENSDARP00000116409 | Clusterin-associated protein 1 homolog; Required for cilia biogenesis and maintenance in the kidney, the lateral line organ and eye. Appears to function within the multiple intraflagellar transport complex B (IFT-B). Belongs to the CLUAP1 family. | Intraflagellar transport 80 homolog (Chlamydomonas). | 0.995 |
cluap1 | ift81 | ENSDARP00000101015 | ENSDARP00000015953 | Clusterin-associated protein 1 homolog; Required for cilia biogenesis and maintenance in the kidney, the lateral line organ and eye. Appears to function within the multiple intraflagellar transport complex B (IFT-B). Belongs to the CLUAP1 family. | Intraflagellar transport 81 homolog. | 0.987 |
cluap1 | ift88 | ENSDARP00000101015 | ENSDARP00000034047 | Clusterin-associated protein 1 homolog; Required for cilia biogenesis and maintenance in the kidney, the lateral line organ and eye. Appears to function within the multiple intraflagellar transport complex B (IFT-B). Belongs to the CLUAP1 family. | Intraflagellar transport 88 homolog. | 0.994 |
cluap1 | traf3ip1 | ENSDARP00000101015 | ENSDARP00000002437 | Clusterin-associated protein 1 homolog; Required for cilia biogenesis and maintenance in the kidney, the lateral line organ and eye. Appears to function within the multiple intraflagellar transport complex B (IFT-B). Belongs to the CLUAP1 family. | TRAF3-interacting protein 1; Plays an inhibitory role on IL13 signaling by binding to IL13RA1 and recruits TRAF3 and DISC1 to the microtubules. Involved in the regulation of microtubule cytoskeleton organization. Is a negative regulator of microtubule stability, acting through the control of MAP4 levels. Involved in ciliogenesis (By similarity). | 0.992 |
cluap1 | ttc26 | ENSDARP00000101015 | ENSDARP00000032176 | Clusterin-associated protein 1 homolog; Required for cilia biogenesis and maintenance in the kidney, the lateral line organ and eye. Appears to function within the multiple intraflagellar transport complex B (IFT-B). Belongs to the CLUAP1 family. | Intraflagellar transport protein 56; Component of the intraflagellar transport (IFT) complex B required for transport of proteins in the motile cilium. Required for transport of specific ciliary cargo proteins related to motility, while it is neither required for IFT complex B assembly or motion nor for cilium assembly. Plays a key role in maintaining the integrity of the IFT complex B and the proper ciliary localization of the IFT complex B components. Essential for maintaining proper microtubule organization within the ciliary axoneme (By similarity). Belongs to the IFT56 family. | 0.990 |
ift172 | cluap1 | ENSDARP00000061333 | ENSDARP00000101015 | Intraflagellar transport protein 172 homolog; Required for the maintenance and formation of cilia. | Clusterin-associated protein 1 homolog; Required for cilia biogenesis and maintenance in the kidney, the lateral line organ and eye. Appears to function within the multiple intraflagellar transport complex B (IFT-B). Belongs to the CLUAP1 family. | 0.993 |
ift172 | ift20 | ENSDARP00000061333 | ENSDARP00000145296 | Intraflagellar transport protein 172 homolog; Required for the maintenance and formation of cilia. | Intraflagellar transport protein 20 homolog; Involved in ciliary process assembly. May play a role in the trafficking of ciliary membrane proteins from the Golgi complex to the cilium. Regulates the platelet-derived growth factor receptor-alpha (PDGFRA) signaling pathway. Plays an important role in spermatogenesis, particularly spermiogenesis, when germ cells form flagella. | 0.991 |
ift172 | ift46 | ENSDARP00000061333 | ENSDARP00000083038 | Intraflagellar transport protein 172 homolog; Required for the maintenance and formation of cilia. | Intraflagellar transport protein 46 homolog; Forms part of a complex involved in intraflagellar transport (IFT), the bi-directional movement of particles required for the assembly, maintenance and functioning of primary cilia. Plays a role in early embryonic development; Belongs to the IFT46 family. | 0.997 |
ift172 | ift52 | ENSDARP00000061333 | ENSDARP00000066190 | Intraflagellar transport protein 172 homolog; Required for the maintenance and formation of cilia. | Intraflagellar transport 52 homolog (Chlamydomonas). | 0.999 |
ift172 | ift57 | ENSDARP00000061333 | ENSDARP00000013774 | Intraflagellar transport protein 172 homolog; Required for the maintenance and formation of cilia. | Intraflagellar transport protein 57 homolog; Required for the formation of cilia. Essential for differentiation and survival of sensory neurons. May also have pro- apoptotic function. | 0.999 |
ift172 | ift80 | ENSDARP00000061333 | ENSDARP00000116409 | Intraflagellar transport protein 172 homolog; Required for the maintenance and formation of cilia. | Intraflagellar transport 80 homolog (Chlamydomonas). | 0.998 |
ift172 | ift81 | ENSDARP00000061333 | ENSDARP00000015953 | Intraflagellar transport protein 172 homolog; Required for the maintenance and formation of cilia. | Intraflagellar transport 81 homolog. | 0.999 |
ift172 | ift88 | ENSDARP00000061333 | ENSDARP00000034047 | Intraflagellar transport protein 172 homolog; Required for the maintenance and formation of cilia. | Intraflagellar transport 88 homolog. | 0.999 |
ift172 | traf3ip1 | ENSDARP00000061333 | ENSDARP00000002437 | Intraflagellar transport protein 172 homolog; Required for the maintenance and formation of cilia. | TRAF3-interacting protein 1; Plays an inhibitory role on IL13 signaling by binding to IL13RA1 and recruits TRAF3 and DISC1 to the microtubules. Involved in the regulation of microtubule cytoskeleton organization. Is a negative regulator of microtubule stability, acting through the control of MAP4 levels. Involved in ciliogenesis (By similarity). | 0.998 |
ift172 | ttc26 | ENSDARP00000061333 | ENSDARP00000032176 | Intraflagellar transport protein 172 homolog; Required for the maintenance and formation of cilia. | Intraflagellar transport protein 56; Component of the intraflagellar transport (IFT) complex B required for transport of proteins in the motile cilium. Required for transport of specific ciliary cargo proteins related to motility, while it is neither required for IFT complex B assembly or motion nor for cilium assembly. Plays a key role in maintaining the integrity of the IFT complex B and the proper ciliary localization of the IFT complex B components. Essential for maintaining proper microtubule organization within the ciliary axoneme (By similarity). Belongs to the IFT56 family. | 0.992 |