STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
casrCalcium-sensing receptor. (946 aa)    
Predicted Functional Partners:
gprc6a
G-protein coupled receptor family C group 6 member A; Olfactory receptor that is activated by amino acids that act as potent odorants in fish. Displays preference for acidic amino acids such as Glu over basic amino acids; Belongs to the G-protein coupled receptor 3 family.
     
0.915
olfcb1
Olfactory receptor C family, b1.
   
 
0.915
plcb3
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes.
     
 0.907
Plcb2
Phosphoinositide phospholipase C.
     
 0.902
PLCB4
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes.
     
 0.901
ENSDARP00000148213
PH_14 domain-containing protein.
     
 0.900
ap2s1
AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.
      
 0.752
gcm2
Glial cells missing homolog 2 (Drosophila).
   
 
 0.731
gpr158a
G protein-coupled receptor 158a.
      
 0.721
trpv6
Transient receptor potential cation channel, subfamily V, member 6; Belongs to the transient receptor (TC 1.A.4) family.
      
 0.690
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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