Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
coro2aCoronin; Belongs to the WD repeat coronin family. (533 aa)    
Predicted Functional Partners:
irgf3
Immunity-related GTPase family, f3.
   
 
 0.847
irgq1
Immunity-related GTPase family, q1.
   
 
 0.847
LOC100332723
Uncharacterized protein.
   
 
 0.806
cfl1l
Cofilin 1 (non-muscle),-like; Belongs to the actin-binding proteins ADF family.
   
 0.609
cfl1
Muscle cofilin 2; Belongs to the actin-binding proteins ADF family.
   
 0.594
cfl2
Cofilin 2 (Muscle); Belongs to the actin-binding proteins ADF family.
   
 0.522
scinlb
Scinderin-like b.
    
 
 0.485
scin
Scinderin.
    
 
 0.484
fpgs
Folylpolyglutamate synthase; Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis; Belongs to the folylpolyglutamate synthase family.
    
 0.478
scinla
Scinderin-like a.
    
 
 0.473
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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