Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
lbx1bLadybird homeobox 1b. (265 aa)    
Predicted Functional Partners:
fbxw4
F-box and WD repeat domain-containing 4.
      
 0.720
dpcd
Protein DPCD; Belongs to the DPCD family.
      
 0.711
lmx1ba
LIM homeobox transcription factor 1, beta a.
    
 
 0.681
poll
Polymerase (DNA directed), lambda; Belongs to the DNA polymerase type-X family.
      
 0.675
skor1a
SKI family transcriptional corepressor 1a.
    
 
 0.626
lmx1bb
LIM homeobox transcription factor 1, beta 1.
    
 
 0.610
skor1b
SKI family transcriptional corepressor 1 homolog-B; May inhibit BMP signaling; Belongs to the SKI family.
    
 
 0.597
ebf1a
Transcription factor COE1-A; Transcriptional activator; Belongs to the COE family.
      
 0.560
skor2
SKI family transcriptional corepressor 2.
    
 
 0.545
zgc:65851
Zgc:65851; Belongs to the intermediate filament family.
    
 
 0.504
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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