STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
lipiaLipase member H; Hydrolyzes specifically phosphatidic acid (PA) to produce lysophosphatidic acid (LPA); Belongs to the AB hydrolase superfamily. Lipase family. (454 aa)    
Predicted Functional Partners:
pnpla7b
Patatin-like phospholipase domain-containing 7b.
    
 
 0.811
lipib
Lipase, member Ib.
  
  
 
0.804
pnpla4
Patatin-like phospholipase domain-containing 4.
   
  
 0.744
pla2g15
Phospholipase A2, group XV.
   
  
 0.743
fitm1
Fat storage-inducing transmembrane protein 1; Plays an important role in lipid droplet accumulation. Belongs to the FIT family.
      
 0.719
prxl2b
Prostamide/prostaglandin F synthase; Catalyzes the reduction of prostaglandin-ethanolamide H(2) (prostamide H(2)) to prostamide F(2alpha) with NADPH as proton donor. Also able to reduce prostaglandin H(2) to prostaglandin F(2alpha) (By similarity); Belongs to the peroxiredoxin-like PRXL2 family. Prostamide/prostaglandin F synthase subfamily.
      
 0.661
abhd4
Abhydrolase domain-containing 4.
   
  
 0.630
fbp1a
Fructose-1,6-bisphosphatase 1a; Belongs to the FBPase class 1 family.
   
  
 0.571
E7FAQ0_DANRE
Metalloendopeptidase.
      
 0.551
LOC100003133
Metalloendopeptidase.
      
 0.551
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.