Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-occurrence
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[Homology]
Score
adgrl4Adhesion G protein-coupled receptor L4; Orphan receptor that plays a role in vessel formation. Belongs to the G-protein coupled receptor 2 family. Adhesion G-protein coupled receptor (ADGR) subfamily. (735 aa)    
Predicted Functional Partners:
hsd17b14
Hydroxysteroid (17-beta) dehydrogenase 14.
      
 0.717
miga1
Mitoguardin 1; Regulator of mitochondrial fusion: acts by forming homo- and heterodimers at the mitochondrial outer membrane and facilitating the formation of pld6/MitoPLD dimers. May act by regulating phospholipid metabolism via pld6/MitoPLD.
      
 0.697
zzz3
Zinc finger, ZZ-type-containing 3.
      
 0.669
clec14a
C-type lectin domain-containing 14A.
   
  
 0.646
cd63
Tetraspanin.
    
   0.637
myct1a
Myc target protein 1 homolog.
   
  
 0.632
ptgfr
Prostaglandin F receptor (FP); Belongs to the G-protein coupled receptor 1 family.
      
 0.603
zgc:173729
Zgc:173729; Belongs to the serpin family.
      
 0.594
serpinb1l4
Serpin peptidase inhibitor, clade B (ovalbumin), member 1,-like 4; Belongs to the serpin family.
      
 0.594
mospd1
Motile sperm domain-containing 1.
    
 
 0.593
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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