STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cldn12Claudin 12 isoform fc43a12. (341 aa)    
Predicted Functional Partners:
mrpl20
Mitochondrial ribosomal protein L20; Belongs to the bacterial ribosomal protein bL20 family.
  
 
 0.886
mrpl27
Mitochondrial ribosomal protein L27.
  
 
 0.884
aldh18a1
Delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family.
  
 
 0.883
E7F2E7_DANRE
Si:zfos-1192g2.3.
  
 
 0.871
mrpl21
Mitochondrial ribosomal protein L21.
  
 
 0.852
cldn1
Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.
      
 0.850
mrpl17
Mitochondrial ribosomal protein L17; Belongs to the bacterial ribosomal protein bL17 family.
   
 
 0.841
mrpl32
Mitochondrial ribosomal protein L32.
  
 
 0.840
cldn15a
Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.
      
 0.826
cldnc
Claudin c.
   
  
 0.804
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.