Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
cyb5r3NADH-cytochrome b5 reductase; Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family. (298 aa)    
Predicted Functional Partners:
cyb5b
Cytochrome b5 type B; Belongs to the cytochrome b5 family.
   
 0.996
cyb5a
Cytochrome b5 type A (microsomal); Belongs to the cytochrome b5 family.
   
 0.995
cyb5r4
Cytochrome b5 reductase 4; NADH-cytochrome b5 reductase involved in endoplasmic reticulum stress response pathway; Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
   
 0.960
suox
Sulfite oxidase.
 
 
 
 0.948
cmah
Cytidine monophosphate-N-acetylneuraminic acid hydroxylase; Sialic acids are components of carbohydrate chains of glycoconjugates and are involved in cell-cell recognition and cell- pathogen interactions. Catalyzes the conversion of CMP-N- acetylneuraminic acid (CMP-Neu5Ac) into its hydroxylated derivative CMP-N-glycolylneuraminic acid (CMP-Neu5Gc), a sialic acid abundantly expressed at the surface of many cells.
     
 0.948
cyb5r2
NADH-cytochrome b5 reductase 2; NADH-cytochrome b5 reductases are involved in desaturation and elongation of fatty acids, cholesterol biosynthesis and drug metabolism; Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
     
  0.944
umps
Uridine monophosphate synthetase.
  
 
 0.870
dhodh
Dihydroorotate dehydrogenase (quinone), mitochondrial; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
  
 0.824
dpydb
Dihydropyrimidine dehydrogenase [NADP(+)]; Involved in pyrimidine base degradation. Catalyzes the reduction of uracil and thymine (By similarity); Belongs to the dihydropyrimidine dehydrogenase family.
  
 0.769
dpyda.1
Dihydropyrimidine dehydrogenase a, tandem duplicate 1.
  
 0.769
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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