Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
man2b1Alpha-mannosidase. (982 aa)    
Predicted Functional Partners:
man2c1
Mannosidase, alpha, class 2C, member 1.
     
 0.985
man2b2
Alpha-mannosidase.
     
0.958
manba
Mannosidase, beta A, lysosomal.
   
 
 0.877
mgat1b
Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase b.
   
 
 0.856
naga
Alpha-galactosidase.
   
 
 0.826
zanl
Zonadhesin,-like.
      
 0.720
man2a1
Alpha-mannosidase.
     
0.699
man2a2
Alpha-mannosidase.
     
0.659
siae
Sialic acid acetylesterase.
    
 
 0.646
gla
Alpha-galactosidase.
   
 
 0.641
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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