Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
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Co-expression
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[Homology]
Score
cetn3Centrin 3. (167 aa)    
Predicted Functional Partners:
poc5
POC5 centriolar protein homolog (Chlamydomonas).
    
 
 0.991
eny2
Transcription and mRNA export factor ENY2; Involved in mRNA export coupled transcription activation by association with both the TREX-2 and the SAGA complexes. The transcription regulatory histone acetylation (HAT) complex SAGA is a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates in a subcomplex that specifically deubiquitinates histones. The SAGA complex is recruited to specific gene promoters by activators, where it is required for transcription. The TREX-2 complex [...]
   
 
 0.948
mcm3ap
Minichromosome maintenance complex component 3-associated protein.
    
 
 0.931
sfi1
SFI1 centrin-binding protein.
   
 
 0.919
pa2g4b
Proliferation-associated 2G4, b.
    
 
 0.891
pa2g4a
Novel protein similar to human proliferation-associated 2G4 protein (PA2G4).
    
 
 0.891
pcid2
PCI domain-containing protein 2; Belongs to the CSN12 family.
    
 
 0.877
xpc
Xeroderma pigmentosum, complementation group C.
    
 
 0.834
ttk
Dual specificity protein kinase Ttk; Phosphorylates proteins on serine, threonine, and tyrosine (By similarity). Involved in mitotic cell cycle checkpoint control. Required for fin and heart regeneration. Required to prevent chromosome segregation errors during meiosis. Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
    
 
 0.831
ribc2
RIB43A domain with coiled-coils 2.
    
 0.799
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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