Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
lipibLipase, member Ib. (445 aa)    
Predicted Functional Partners:
ccn1l1
Cellular communication network factor 1,-like 1.
   
  
 0.951
adamtsl7
ADAMTS-like 7.
    
 
 0.887
cidec
Cell death-inducing DFFA-like effector c.
      
 0.816
fosl1b
FOS-like 1, AP-1 transcription factor subunit b.
    
 0.807
cpa4
Carboxypeptidase A4.
    
 
 0.735
rpe65a
Retinoid isomerohydrolase; Plays important roles in the production of 11-cis retinal and in visual pigment regeneration. Capable of catalyzing the isomerization of lutein to meso-zeaxanthin an eye-specific carotenoid (By similarity).
      
 0.662
cldn7b
Claudin-7-B; Plays a major role in tight junction-specific obliteration of the intercellular space; Belongs to the claudin family.
      
 0.596
lepb
Leptin b.
   
  
 0.580
il11a
Interleukin 11a.
      
 0.570
dkk1a
Dickkopf WNT-signaling pathway inhibitor 1a.
      
 0.483
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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