STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
kcnk5bPotassium channel, subfamily K, member 5b; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. (448 aa)    
Predicted Functional Partners:
slc12a7a
Solute carrier family 12 member 7a.
   
  
 0.866
cx43
Gap junction alpha-1 protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. Plays an essential role in gap junction communication in the ventricles (By similarity); Belongs to the connexin family. Alpha-type (group II) subfamily.
      
 0.807
cx39.4
Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
      
 0.744
evx1
Even-skipped homeobox 1.
   
  
 0.739
kcnj1b
Potassium inwardly rectifying channel subfamily J member 1b.
      
 0.679
kcnj13
Potassium inwardly rectifying channel subfamily J member 13.
   
  
 0.678
evx1-2
Even-skipped homeobox 1.
   
  
 0.672
rpz
Protein rapunzel.
      
 0.670
gja5b
Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
      
 0.669
F1Q5G8_DANRE
Si:dkey-49n23.1; Belongs to the semaphorin family.
      
 0.665
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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