node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
fgf8a | her1 | ENSDARP00000018653 | ENSDARP00000027076 | Fibroblast growth factor 8; Plays an important role in the regulation of embryonic development, cell proliferation, cell differentiation and cell migration (By similarity). Required for Kupffer's vesicle ciliogenesis. | Hairy-related 1. | 0.434 |
fgf8a | meox1 | ENSDARP00000018653 | ENSDARP00000096438 | Fibroblast growth factor 8; Plays an important role in the regulation of embryonic development, cell proliferation, cell differentiation and cell migration (By similarity). Required for Kupffer's vesicle ciliogenesis. | Homeobox protein MOX-1; Mesodermal transcription factor that plays a key role in somitogenesis and is specifically required for sclerotome development. Required for maintenance of the sclerotome polarity and formation of the cranio-cervical joints. Binds specifically to the promoter of target genes and regulates their expression. Required for hematopoietic stem cell (HSCs) induction via its role in somitogenesis: specification of HSCs occurs via the deployment of a specific endothelial precursor population, which arises within a sub-compartment of the somite named endotome. Acts by med [...] | 0.431 |
fgf8a | mespab | ENSDARP00000018653 | ENSDARP00000090346 | Fibroblast growth factor 8; Plays an important role in the regulation of embryonic development, cell proliferation, cell differentiation and cell migration (By similarity). Required for Kupffer's vesicle ciliogenesis. | Mesoderm posterior ab. | 0.584 |
fgf8a | mespba | ENSDARP00000018653 | ENSDARP00000139800 | Fibroblast growth factor 8; Plays an important role in the regulation of embryonic development, cell proliferation, cell differentiation and cell migration (By similarity). Required for Kupffer's vesicle ciliogenesis. | Mesoderm posterior ba. | 0.431 |
fgf8a | msgn1 | ENSDARP00000018653 | ENSDARP00000094435 | Fibroblast growth factor 8; Plays an important role in the regulation of embryonic development, cell proliferation, cell differentiation and cell migration (By similarity). Required for Kupffer's vesicle ciliogenesis. | Mesogenin-1; Involved in specifying the paraxial, but not dorsal, mesoderm. May regulate the expression of T-box transcription factors required for mesoderm formation and differentiation (By similarity). | 0.460 |
fgf8a | pax3a | ENSDARP00000018653 | ENSDARP00000037761 | Fibroblast growth factor 8; Plays an important role in the regulation of embryonic development, cell proliferation, cell differentiation and cell migration (By similarity). Required for Kupffer's vesicle ciliogenesis. | Transcription factor PAX3. | 0.661 |
fgf8a | tbx6 | ENSDARP00000018653 | ENSDARP00000015108 | Fibroblast growth factor 8; Plays an important role in the regulation of embryonic development, cell proliferation, cell differentiation and cell migration (By similarity). Required for Kupffer's vesicle ciliogenesis. | T-box transcription factor TBX6; T-box transcription factor involved in the development of paraxial mesoderm. | 0.858 |
fgf8a | uncx4.1 | ENSDARP00000018653 | ENSDARP00000055008 | Fibroblast growth factor 8; Plays an important role in the regulation of embryonic development, cell proliferation, cell differentiation and cell migration (By similarity). Required for Kupffer's vesicle ciliogenesis. | Homeobox protein unc-4 homolog; Transcription factor involved in somitogenesis and neurogenesis; Belongs to the paired homeobox family. Unc-4 subfamily. | 0.562 |
her1 | fgf8a | ENSDARP00000027076 | ENSDARP00000018653 | Hairy-related 1. | Fibroblast growth factor 8; Plays an important role in the regulation of embryonic development, cell proliferation, cell differentiation and cell migration (By similarity). Required for Kupffer's vesicle ciliogenesis. | 0.434 |
her1 | mespab | ENSDARP00000027076 | ENSDARP00000090346 | Hairy-related 1. | Mesoderm posterior ab. | 0.852 |
her1 | mespba | ENSDARP00000027076 | ENSDARP00000139800 | Hairy-related 1. | Mesoderm posterior ba. | 0.859 |
her1 | msgn1 | ENSDARP00000027076 | ENSDARP00000094435 | Hairy-related 1. | Mesogenin-1; Involved in specifying the paraxial, but not dorsal, mesoderm. May regulate the expression of T-box transcription factors required for mesoderm formation and differentiation (By similarity). | 0.604 |
her1 | ripply1 | ENSDARP00000027076 | ENSDARP00000154427 | Hairy-related 1. | Protein ripply1; Plays a role in somitogenesis. Essential for transcriptional repression of the segmental patterning genes, thus terminating the segmentation program in the presomitic mesoderm, and also required for the maintenance of rostrocaudal polarity in somites. | 0.748 |
her1 | ripply2 | ENSDARP00000027076 | ENSDARP00000094407 | Hairy-related 1. | Protein ripply2; Plays a role in somitogenesis. Required for somite segregation and establishment of rostrocaudal polarity in somites (By similarity). | 0.699 |
her1 | tbx6 | ENSDARP00000027076 | ENSDARP00000015108 | Hairy-related 1. | T-box transcription factor TBX6; T-box transcription factor involved in the development of paraxial mesoderm. | 0.859 |
her1 | uncx4.1 | ENSDARP00000027076 | ENSDARP00000055008 | Hairy-related 1. | Homeobox protein unc-4 homolog; Transcription factor involved in somitogenesis and neurogenesis; Belongs to the paired homeobox family. Unc-4 subfamily. | 0.672 |
meox1 | fgf8a | ENSDARP00000096438 | ENSDARP00000018653 | Homeobox protein MOX-1; Mesodermal transcription factor that plays a key role in somitogenesis and is specifically required for sclerotome development. Required for maintenance of the sclerotome polarity and formation of the cranio-cervical joints. Binds specifically to the promoter of target genes and regulates their expression. Required for hematopoietic stem cell (HSCs) induction via its role in somitogenesis: specification of HSCs occurs via the deployment of a specific endothelial precursor population, which arises within a sub-compartment of the somite named endotome. Acts by med [...] | Fibroblast growth factor 8; Plays an important role in the regulation of embryonic development, cell proliferation, cell differentiation and cell migration (By similarity). Required for Kupffer's vesicle ciliogenesis. | 0.431 |
meox1 | mespab | ENSDARP00000096438 | ENSDARP00000090346 | Homeobox protein MOX-1; Mesodermal transcription factor that plays a key role in somitogenesis and is specifically required for sclerotome development. Required for maintenance of the sclerotome polarity and formation of the cranio-cervical joints. Binds specifically to the promoter of target genes and regulates their expression. Required for hematopoietic stem cell (HSCs) induction via its role in somitogenesis: specification of HSCs occurs via the deployment of a specific endothelial precursor population, which arises within a sub-compartment of the somite named endotome. Acts by med [...] | Mesoderm posterior ab. | 0.596 |
meox1 | mespba | ENSDARP00000096438 | ENSDARP00000139800 | Homeobox protein MOX-1; Mesodermal transcription factor that plays a key role in somitogenesis and is specifically required for sclerotome development. Required for maintenance of the sclerotome polarity and formation of the cranio-cervical joints. Binds specifically to the promoter of target genes and regulates their expression. Required for hematopoietic stem cell (HSCs) induction via its role in somitogenesis: specification of HSCs occurs via the deployment of a specific endothelial precursor population, which arises within a sub-compartment of the somite named endotome. Acts by med [...] | Mesoderm posterior ba. | 0.586 |
meox1 | msgn1 | ENSDARP00000096438 | ENSDARP00000094435 | Homeobox protein MOX-1; Mesodermal transcription factor that plays a key role in somitogenesis and is specifically required for sclerotome development. Required for maintenance of the sclerotome polarity and formation of the cranio-cervical joints. Binds specifically to the promoter of target genes and regulates their expression. Required for hematopoietic stem cell (HSCs) induction via its role in somitogenesis: specification of HSCs occurs via the deployment of a specific endothelial precursor population, which arises within a sub-compartment of the somite named endotome. Acts by med [...] | Mesogenin-1; Involved in specifying the paraxial, but not dorsal, mesoderm. May regulate the expression of T-box transcription factors required for mesoderm formation and differentiation (By similarity). | 0.579 |