Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
tbccTubulin folding cofactor C. (350 aa)    
Predicted Functional Partners:
tbcd
Tubulin folding cofactor D.
    
 
 0.989
tbce
Tubulin-specific chaperone E; Tubulin-folding protein; involved in the second step of the tubulin folding pathway.
    
 
 0.945
arl2
ADP-ribosylation factor-like 2; Belongs to the small GTPase superfamily. Arf family.
    
 
 0.944
tbcb
Tubulin folding cofactor B.
      
 0.865
arl3b
ADP-ribosylation factor-like protein 3; Small GTP-binding protein which cycles between an inactive GDP-bound and an active GTP-bound form, and the rate of cycling is regulated by guanine nucleotide exchange factors (GEF) and GTPase- activating proteins (GAP). Required for normal cytokinesis and cilia signaling. Required for targeting proteins to the ciliary membrane by releasing myristoylated protein from unc119 cargo adapters into the cilium (By similarity).
    
 
 0.777
arl3a
ADP ribosylation factor-like GTPase 3a; Belongs to the small GTPase superfamily. Arf family.
    
 
 0.744
tbca
Tubulin-specific chaperone A; Belongs to the TBCA family.
      
 0.694
tbcela
Tubulin folding cofactor E-like a.
      
 0.683
tbcelb
Tubulin folding cofactor E-like b.
      
 0.683
skp1
S-phase kinase-associated protein 1A; Belongs to the SKP1 family.
      
 0.601
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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