Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
commd2COMM domain-containing 2. (199 aa)    
Predicted Functional Partners:
commd8
COMM domain-containing 8.
   
 0.999
commd3
COMM domain-containing 3.
   
 0.998
ccdc22
Coiled-coil domain-containing protein 22; May be involved in regulation of NF-kappa-B signaling. May be involved in copper-dependent atp7a trafficking between the trans-Golgi network and vesicles in the cell periphery (By similarity).
    
 0.998
commd4
COMM domain-containing 4.
   
 0.998
commd9
Si:ch211-154e15.3 protein.
   
 0.997
commd1
Copper metabolism (Murr1) domain-containing 1.
    
 0.997
commd6
COMM domain-containing 6.
   
 0.997
ccdc93
Coiled-coil domain-containing 93.
    
 
 0.996
dennd10
DENN domain-containing protein 10; Guanine nucleotide exchange factor (GEF) which may be involved in the regulation of late endocytic pathway homeostasis, including endosomal positioning, maturation and secretion. Belongs to the DENND10 family.
    
 
 0.995
vps26c
VPS26 endosomal protein sorting factor C.
    
 
 0.992
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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