STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cpCeruloplasmin; Belongs to the multicopper oxidase family. (1087 aa)    
Predicted Functional Partners:
slc40a1
Solute carrier family 40 member 1; May be involved in iron export and also in transfer of iron between maternal and fetal circulation.
   
 0.959
hmox1a
Heme oxygenase; Heme oxygenase cleaves the heme ring at the alpha methene bridge to form biliverdin. Biliverdin is subsequently converted to bilirubin by biliverdin reductase.
   
 0.941
fxn
Frataxin.
     
 0.935
fech
Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX.
   
 
 0.932
hmox2b
Heme oxygenase 2b.
    
 0.913
hmox2a
Heme oxygenase; Heme oxygenase cleaves the heme ring at the alpha methene bridge to form biliverdin. Biliverdin is subsequently converted to bilirubin by biliverdin reductase.
    
 0.913
atp7a
ATPase copper-transporting alpha.
  
 
 0.850
atp7b
ATPase copper-transporting beta.
  
 
 0.838
hpxa
Hemopexin; Binds heme and transports it to the liver for breakdown and iron recovery, after which the free hemopexin returns to the circulation.
   
 
 0.677
atox1
Antioxidant 1 copper chaperone.
      
 0.672
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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