STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
eif4e3Eukaryotic translation initiation factor 4E type 3; Recognizes and binds the 7-methylguanosine-containing mRNA cap during an early step in the initiation of protein synthesis. Belongs to the eukaryotic initiation factor 4E family. (224 aa)    
Predicted Functional Partners:
eif4g2b
Eukaryotic translation initiation factor 4, gamma 2b.
   
 0.861
rnmt
mRNA cap guanine-N7 methyltransferase; Catalytic subunit of the mRNA-capping methyltransferase RNMT:RAMAC complex that methylates the N7 position of the added guanosine to the 5'-cap structure of mRNAs. Binds RNA containing 5'- terminal GpppC; Belongs to the class I-like SAM-binding methyltransferase superfamily. mRNA cap 0 methyltransferase family.
   
 0.812
eif4e1b
Eukaryotic translation initiation factor 4E-1B; Does not appear to be a mRNA-cap-binding protein.
     
0.781
eif4g1a
Eukaryotic translation initiation factor 4 gamma, 1a.
   
 0.779
eif4g3b
Eukaryotic translation initiation factor 4 gamma, 3b.
   
 0.779
ENSDARP00000135501
MIF4G domain-containing protein.
   
 0.779
eif4g3a
Eukaryotic translation initiation factor 4 gamma, 3a.
   
 0.779
wu:fb16f03
Uncharacterized protein.
   
 0.779
eif4ea
Eukaryotic translation initiation factor 4E-1A; Recognizes and binds the 7-methylguanosine-containing mRNA cap during an early step in the initiation of protein synthesis and facilitates ribosome binding by inducing the unwinding of the mRNAs secondary structures.
     
0.775
eif4g2a
Eukaryotic translation initiation factor 4, gamma 2a.
   
 0.773
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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