Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
prdm12bPR domain zinc finger protein 12; Involved in the positive regulation of histone H3-K9 dimethylation; Belongs to the class V-like SAM-binding methyltransferase superfamily. (366 aa)    
Predicted Functional Partners:
en1b
Homeobox protein engrailed-like.
      
 0.781
mcf2a
MCF.2 cell line-derived-transforming sequence a.
      
 0.713
hmgxb4a
HMG box domain-containing 4a.
      
 0.713
p2rx3b
P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel.
      
 0.701
prdm8
PR domain-containing 8.
   
  
 0.695
stk32a
Serine/threonine kinase 32A.
   
  
 0.611
megf6a
Multiple EGF-like-domains 6a.
    
 
 0.602
bhlhe22
Basic helix-loop-helix family, member e22.
   
  
 0.585
pkdcca
Protein kinase domain-containing, cytoplasmic a.
    
 
 0.568
dbx1a
Homeobox protein DBX1-A; Belongs to the H2.0 homeobox family.
   
  
 0.565
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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