STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
prdm12bPR domain zinc finger protein 12; Involved in the positive regulation of histone H3-K9 dimethylation; Belongs to the class V-like SAM-binding methyltransferase superfamily. (366 aa)    
Predicted Functional Partners:
en1b
Homeobox protein engrailed-like.
   
  
 0.835
hmgxb4a
HMG box domain-containing 4a.
      
 0.728
mcf2a
MCF.2 cell line-derived-transforming sequence a.
      
 0.722
prdm8
PR domain-containing 8.
   
  
 0.696
megf6a
Multiple EGF-like-domains 6a.
    
 
 0.646
pkdcca
Protein kinase domain-containing, cytoplasmic a.
    
 
 0.638
ehmt2
Euchromatic histone-lysine N-methyltransferase 2.
    
 
 0.608
bhlhe22
Basic helix-loop-helix family, member e22.
   
  
 0.577
dbx2
Homeobox domain-containing protein.
   
  
 0.568
irx3a
Iroquois 3 homeobox protein.
   
 
 0.523
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
Server load: low (28%) [HD]