Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
plekhb2Pleckstrin homology domain-containing, family B (evectins) member 2. (223 aa)    
Predicted Functional Partners:
klhl30
Kelch-like family member 30.
      
 0.645
wdr33
WD repeat domain 33.
      
 0.636
alyref
Aly/REF export factor.
      
 0.614
prpf40a
PRP40 pre-mRNA processing factor 40 homolog A (Yeast).
      
 0.606
nif3l1
NIF3-like protein 1; May function as a transcriptional corepressor through its interaction with COPS2, negatively regulating the expression of genes involved in neuronal differentiation.
      
 0.482
sat1b
Spermidine/spermine N1-acetyl transferase 1.
      
 0.455
sat1a.1
Spermidine/spermine N1-acetyltransferase 1a, duplicate 1.
      
 0.455
sat1a.2
Spermidine/spermine N1-acetyltransferase 1a, duplicate 2.
      
 0.455
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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