Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
naa15aN(alpha)-acetyltransferase 15, NatA auxiliary subunit a. (867 aa)    
Predicted Functional Partners:
naa50
N-alpha-acetyltransferase 50; N-alpha-acetyltransferase that acetylates the N-terminus of proteins that retain their initiating methionine (By similarity). Has a broad substrate specificity: able to acetylate the initiator methionine of most peptides, except for those with a proline in second position (By similarity). Also displays N-epsilon-acetyltransferase activity by mediating acetylation of the side chain of specific lysines on proteins (By similarity). The relevance of N-epsilon-acetyltransferase activity is however unclear (By similarity). Required for sister chromatid cohesion [...]
   
 0.992
naa10
N(alpha)-acetyltransferase 10, NatA catalytic subunit.
   
 0.989
scyl1
SCY1-like, kinase-like 1.
   
  
 0.959
flrt1b
Fibronectin leucine-rich transmembrane protein 1b.
      
 0.953
naa15b
N(alpha)-acetyltransferase 15, NatA auxiliary subunit b.
  
 
0.906
hypk
Huntingtin-interacting protein K.
    
 
 0.892
naa25
N(alpha)-acetyltransferase 25, NatB auxiliary subunit.
   
 
 0.860
macrod1
Mono-ADP ribosylhydrolase 1.
    
 
 0.837
elf2a
E74-like factor 2a (ets domain transcription factor).
   
  
 0.820
naa20
N-alpha-acetyltransferase 20; Catalytic subunit of the NatB complex which catalyzes acetylation of the N-terminal methionine residues of peptides beginning with Met-Asp, Met-Glu, Met-Asn and Met-Gln. Proteins with cell cycle functions are overrepresented in the pool of NatB substrates. Required for maintaining the structure and function of actomyosin fibers and for proper cellular migration.
   
 0.820
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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